tag:blogger.com,1999:blog-6646099545863113482Thu, 29 Apr 2010 13:45:22 +0000http://www.mitoblog.org/index.phpnoreply@blogger.com (Jason)Blogger33125tag:blogger.com,1999:blog-6646099545863113482.post-3155097701998831463Thu, 29 Apr 2010 13:45:00 +00002010-04-29T09:45:22.292-04:00 This blog is now located at http://blog.mitoblog.org/. You will be automatically redirected in 30 seconds, or you may click here. For feed subscribers, please update your feed subscriptions to http://blog.mitoblog.org/feeds/posts/default. http://www.mitoblog.org/2010/04/this-blog-has-moved.PHPnoreply@blogger.com (Jason)0tag:blogger.com,1999:blog-6646099545863113482.post-7674753141014200574Tue, 13 Apr 2010 17:57:00 +00002010-04-13T14:01:17.175-04:00There is more and more research connecting mitochondrial dysfunction with many other major diseases and illnesses - including autism, parkinson's, alzheimer's, and even some forms of cancer. The link between the mitochondria and other diseases, as well as aging in general, is in its infancy and needs much more research! Not only will this research help us understand many other conditions, but http://www.mitoblog.org/2010/04/mito-aging-process-other-diseases.PHPnoreply@blogger.com (Lisa)0tag:blogger.com,1999:blog-6646099545863113482.post-6987668262410349798Sat, 10 Apr 2010 13:58:00 +00002010-04-10T10:01:50.842-04:00MitoAction.org in conjunction with students from the Center for Digital Imaging Arts at Boston University have put together an informative video that helps explain what happens to cause mitochondrial disease. This is a pretty interesting and informative video that would be great to show to teachers, friends, and family to help explain "mito" in a simple way. While it is not all-encompassing, ithttp://www.mitoblog.org/2010/04/mighty-mitochondria-in-action-video.PHPnoreply@blogger.com (Lisa)0tag:blogger.com,1999:blog-6646099545863113482.post-5306765911192356879Sat, 13 Mar 2010 14:18:00 +00002010-03-13T09:30:13.157-05:00ResearchAutismI'm very happy to report that Autism Speaks is starting to seriously consider mitochondrial dysfunction and its relationship to autism. While the Hannah Poling case initially got everyone jumping up and down about the connection between vaccines and autism, once again, the more important thing that should have come from that case is that Hannah Poling had a diagnosis of mitochondrial dysfunctionhttp://www.mitoblog.org/2010/03/autism-speaks-looking-at-mitochondrial.PHPnoreply@blogger.com (Lisa)0tag:blogger.com,1999:blog-6646099545863113482.post-5695065420780082931Wed, 27 Jan 2010 14:18:00 +00002010-01-28T22:36:58.105-05:00NIHHR 3502S.2858On Thursday, December 10, 2009, Senator Barbara Boxer (D-CA), introduced S. 2858 - “The Brittany Wilkinson Mitochondrial Disease Research and Treatment Enhancement Act of 2009”. Senators Richard Durbin (D-IL), John Kerry (D-MA) and Robert P. Casey (D-PA) all signed on as co-sponsors of the legislation.The house measure is a companion bill, HR 3502, which was introduced by Representative James http://www.mitoblog.org/2010/01/brittany-wilkinson-mitochondrial.PHPnoreply@blogger.com (Lisa)0tag:blogger.com,1999:blog-6646099545863113482.post-6983339091308167939Wed, 27 Jan 2010 14:09:00 +00002010-01-27T09:14:45.738-05:00When I first started this blog, the idea was to put cutting edge information on mitochondrial disease on the site - so that it would be a place that would have all the information on mitochondrial disease in one place. As I have worked on the blog and thought more about it, while I am still going to post information on new research, articles, and all information related to mitochondrial disease, http://www.mitoblog.org/2010/01/taking-blog-to-new-level.PHPnoreply@blogger.com (Lisa)0tag:blogger.com,1999:blog-6646099545863113482.post-6816500382819233674Wed, 27 Jan 2010 14:01:00 +00002010-01-27T09:09:21.253-05:00Fever ManagementAutismIn a recent study, researchers found more evidence to possibly connect autism and mitochondrial disease. The article, Fever Plus Mitochondrial Disease Could Be Risk Factors for Autistic Regression, is not yet fully published, but the abstract indicates a possible link. Their study was based upon twenty-eight (28) patients who fit both the criteria for autism and had confirmed mitochondrial http://www.mitoblog.org/2010/01/autism-and-mitochondrial-disease-link.PHPnoreply@blogger.com (Lisa)0tag:blogger.com,1999:blog-6646099545863113482.post-4058917841666635311Thu, 27 Aug 2009 01:09:00 +00002009-08-26T21:14:12.055-04:00Gene TherapyScientists have successfully tested some germline gene therapy involving replacing genetic mutations in mitochondrial DNA of a mother's egg to produce a disease-free, or genetically proper, egg."In theory, this research has demonstrated it is possible to use this therapy in mothers carrying mitochondrial DNA diseases so that we can prevent those diseases from being passed on to their offspring," http://www.mitoblog.org/2009/08/germline-gene-therapy-could-end.PHPnoreply@blogger.com (Lisa)0tag:blogger.com,1999:blog-6646099545863113482.post-6312865281847589035Sat, 22 Aug 2009 12:17:00 +00002009-08-22T08:21:07.333-04:00For the first time, researchers have now determined that chronic kidney disease/hemodyalisis patients have impaired mitochondrial function. In fact, their conclusion drawn thus far indicates that the mitochondrial dysfunction may be the cause of their disease! You can read about the research here. This is yet another reason why we need to increase research into mitochondrial dysfunction and http://www.mitoblog.org/2009/08/chronic-kidney-disease-linked-to.PHPnoreply@blogger.com (Lisa)0tag:blogger.com,1999:blog-6646099545863113482.post-1513493191206885133Wed, 29 Jul 2009 01:28:00 +00002009-07-28T21:28:23.777-04:00Recent research has confirmed what many mito families already know - mito patients have an increased susceptibility to infection, particularly in the respiratory tract. With the H1N1 (Swine Flu) running rampant around the globe, and as the cold and flu season ramps up in the United States, mito families need to re-evaluate the amount of contact they have with the general public. The flu is http://www.mitoblog.org/2009/07/stress-signals-in-mito-disease-increase.PHPnoreply@blogger.com (Lisa)0tag:blogger.com,1999:blog-6646099545863113482.post-9046298488236368478Sun, 19 Jul 2009 00:58:00 +00002009-07-18T21:06:10.591-04:00Pfizer recently announced that Dimebon (latrepirdine) is in Phase 3 trials and doing well. The drug is targeted to treat Alzheimer's disease, but it may be one that we need to look at for treatment of mitochondrial disease as well.Dimebon, according to Pfizer, is thought to potentially stabilize or improve mitochondrial function in a way that prevents neurons from damage and dysfunction.http://www.mitoblog.org/2009/07/investigational-drug-for-alzheimers.PHPnoreply@blogger.com (Lisa)0tag:blogger.com,1999:blog-6646099545863113482.post-7788704407159328871Fri, 17 Jul 2009 16:20:00 +00002009-07-17T12:22:11.656-04:00On the right side you can now sign up for my RSS feed of MitoBlog! We are gearing up on MitoBlog and want to bring you all the news about mito that is out there! Good news, fundraisers, treatments, therapies, medications and everything else! Leave a comment and let me know what you want to hear about!http://www.mitoblog.org/2009/07/sign-up-for-my-rss-feed.PHPnoreply@blogger.com (Lisa)0tag:blogger.com,1999:blog-6646099545863113482.post-4407701281990143635Fri, 17 Jul 2009 16:02:00 +00002009-07-17T12:09:17.306-04:00Mito TestingMEDomics has started using a new test called MitoDx to detect any and all mutations in any of the 37 identified mitochondrial genes. You can read more about it here. This is supposed to be a new way to help do early detection of mitochondrial disorders that do not require as invasive of testing (as the usual muscle biopsy). While it does detect mutations, it may not identify all with http://www.mitoblog.org/2009/07/new-diagnostic-test-for-mito.PHPnoreply@blogger.com (Lisa)1tag:blogger.com,1999:blog-6646099545863113482.post-5924538513274961304Fri, 17 Jul 2009 15:50:00 +00002009-07-17T11:50:58.530-04:00Penwest Pharmaceuticals has been working on a new mito drug - A0001 - for the treatment of mitochondrial diseases. The Phase 1b Trial of the drug under FDA guidelines went well and they are moving the drug into the next phases of the trial, as they move forward on orphan drug status and closer to an FDA approved medication for mitochondrial disease! The link will take you to the press release http://www.mitoblog.org/2009/07/mito-drug-advances-to-fda-phase-iia.PHPnoreply@blogger.com (Lisa)0tag:blogger.com,1999:blog-6646099545863113482.post-8962731328667320258Mon, 25 May 2009 03:06:00 +00002009-05-24T23:12:49.031-04:00resourcesMitoactionMito Disease managementI found a fabulous resource today while I was researching yet another issue regarding mito and my daughter. Mitoaction has a Clinician's Guide on their website which is a wonderful resource for the patient, caregiver or medical professional. The guide is totally on their site and different sections are easily accessed by clicking on them. You even have an option to print the page/section you http://www.mitoblog.org/2009/05/general-management-of-mitochondrial.PHPnoreply@blogger.com (Lisa)0tag:blogger.com,1999:blog-6646099545863113482.post-5417924029465012827Thu, 07 May 2009 12:36:00 +00002009-05-07T08:51:07.274-04:00organizationsIn my web browsing, I ran across Marcel's Way. Its a very interesting idea and organization that's sole purpose is to support mitochondrial patients and their families in New Hampshire.Some of the interesting things they do are: family vouchers for $5 when a child/patient has a metabolic or mitochondrial appointment at the hospital or if they are admitted to the hospital; grants ranging from http://www.mitoblog.org/2009/05/new-hampshire-organization-helps.PHPnoreply@blogger.com (Lisa)0tag:blogger.com,1999:blog-6646099545863113482.post-8502061021813722575Mon, 04 May 2009 13:20:00 +00002009-05-04T09:24:21.263-04:00Mito EventsThis coming Saturday, May 10th, is the 8th Annual Run Wild for a Cure in Cleveland, Ohio. They will have a 5K event and a 1 mile walk with entertainment, refreshments, a raffle and plenty of fun! The cost ranges from $15 to $25 per person, depending on age, and includes an event tshirt, admission to both the Cleveland Metroparks Zoo and Rainforest for the WHOLE day, and all the extras after the http://www.mitoblog.org/2009/05/mito-events-around-us-ohio.PHPnoreply@blogger.com (Lisa)0tag:blogger.com,1999:blog-6646099545863113482.post-5763023846652343305Wed, 15 Apr 2009 00:55:00 +00002009-04-14T21:21:56.508-04:00NewsweekMagazine ArticlesEpilepsyAs I have posted before, many mitochondrial patients suffer from seizures daily. Epilepsy is finally getting some much-needed publicity in the April 20th edition of Newsweek. You can read the articles on their website which I have linked below.My daughter has suffered from seizures since she was 4 weeks old. The longest she has ever gone without a seizure is 35 days. At this point, she is http://www.mitoblog.org/2009/04/epilepsy-articles-go-mainstream.PHPnoreply@blogger.com (Lisa)1tag:blogger.com,1999:blog-6646099545863113482.post-2755146999006013979Mon, 06 Apr 2009 13:46:00 +00002009-04-06T09:49:08.202-04:00scientific breakthroughAlzheimersWell, its been said before that there is a link between mitochondrial damage and many diseases, but for the first time scientists have proven that damage to parts of the mitochondria will lead to Alzheimer's! You can read the article HERE. This is good news for the mito community! Alzheimers is another "hot disease" out there - like autism and breast cancer. Hopefully this new scientific http://www.mitoblog.org/2009/04/alzheimers-linked-to-mitochondrial.PHPnoreply@blogger.com (Lisa)1tag:blogger.com,1999:blog-6646099545863113482.post-5663949675928613831Tue, 24 Feb 2009 14:21:00 +00002009-02-24T09:28:29.229-05:00EpilepsyToday the FDA posted on its website that treatment with the epilepsy drug Zonegran (generic is zonisamide) can cause metabolic acidosis. Zonegran's label is supposed to be updated with this new warning and recommends that patients have certain blood tests before starting treatment and periodically during treatment to check for acidosis.This new warning is especially important to the http://www.mitoblog.org/2009/02/epilepsy-drug-can-cause-metabolic.PHPnoreply@blogger.com (Lisa)1tag:blogger.com,1999:blog-6646099545863113482.post-1522460315298287873Sun, 22 Feb 2009 19:05:00 +00002009-02-22T18:21:19.431-05:00Mito EventsOn occasion, I will post about events to support mitochondrial disease awareness and fundraising around the country. There are many events every year, and you can also find them listed on my mitoblog calendar. Take a step toward the cure for mitochondrial disease by coming out to these family-friendly events. You will have fun and will more than likely learn something too!On October 17, 2009, http://www.mitoblog.org/2009/02/mito-events-around-us-georgia.PHPnoreply@blogger.com (Lisa)0tag:blogger.com,1999:blog-6646099545863113482.post-5386604520797069926Tue, 03 Feb 2009 12:27:00 +00002009-02-12T19:16:21.736-05:00A leading group of doctors and scientists have banded together and sent a letter to President Obama urging him to include mitochondrial medicine and research among his top health priorities. The letter states, in part, that the mitochondria are important in a large variety of medical conditions and research in this area will greatly improve the health and well-being of millions of American http://www.mitoblog.org/2009/02/letter-to-president-obama.PHPnoreply@blogger.com (Lisa)0tag:blogger.com,1999:blog-6646099545863113482.post-3847921435487215304Wed, 28 Jan 2009 16:36:00 +00002009-01-28T11:43:53.698-05:00UMDFThe United Mitochondrial Disease Foundation (UMDF) has changed and enhanced its membership options effective this month (January, 2009) in order to attract more people to its membership. Prior to this change, it cost fifty dollars ($50.00) to join the UMDF. Now, there are multiple membership options.Everyone can join now under the HOPE membership option, which is free and allows members to havehttp://www.mitoblog.org/2009/01/join-umdf.PHPnoreply@blogger.com (Lisa)2tag:blogger.com,1999:blog-6646099545863113482.post-6026030602779904716Sat, 17 Jan 2009 01:18:00 +00002009-01-16T20:21:04.710-05:00Mito AwarenessAt the end of December, 2008, the Ohio General Assembly voted unanimously to enact a Mitochondrial Disease Awareness Week. The Third week in September is now known as Mitochondrial Disease Awareness Week in Ohio. The Bill states:The third week of September is designated as "Mitochondrial Disease Awareness Week" to raise awareness of the existence of mitochondrial disease and its symptoms.http://www.mitoblog.org/2009/01/ohio-passes-mitochondrial-disease.PHPnoreply@blogger.com (Lisa)1tag:blogger.com,1999:blog-6646099545863113482.post-3890486839355832029Fri, 12 Dec 2008 03:31:00 +00002008-12-21T19:34:13.598-05:00The Vaccine Research Center at Boston University Medical Center through the Department of Pediatrics and Section of Pediatric Infectious Disease has started a pilot study to better understand the safety and efficacy of vaccines in patients who have mitochondrial disorders.This study could prove to be very important. Recently, a high profile vaccine case was in the news. Hannah Poling's case washttp://www.mitoblog.org/2008/12/vaccines-and-mitochondrial-disease.PHPnoreply@blogger.com (Lisa)0